| Trikala town
Modern Trikala, N.W. of Karditsa, is the Homeric Trikki. According to tradition Trikki was the daughter of Pinios. It was also believed that Trikala was the birth-place of Aesculapius; which explains the existence of the oldest sanctuary to the physician -god, the ruins of which are SW of the town. This was a kind of medical centre similar to the ones in Epidaurus and Kos. From here the worship of Aesculapius gradually spread.
Crowned by its Byzantine castle (The Fortress), at the top of a wooded hill, built on the site of the ancient Acropolis, the picturesque city of Trikala lies on St Nicholas heights, by Litheos river, and is divided into two by an old aqueduct. The castle, which is not far from the temple of Aesculapius, was built in Byzantine times on Hellenistic ruins, and underwent many changes under Ottoman rule. From the hill of Profitis Elias (there is a public park and a zoo here) one has a marvellous view of the valley below studded with villages big and small, the river cutting patterns among them. The churches of Agios Demetrios and Agii Anargyri complete the Byzantine flavour of the town.