Makrygianni is a historic and highly significant neighborhood in central Athens, located directly beneath the Acropolis. It is named after General Ioannis Makrygiannis and is one of the most distinctive areas where ancient and modern Athens coexist.

The area hosts some of the city's most important cultural landmarks, including the Acropolis Museum and archaeological sites connecting the Acropolis with the historic center. It also has strong tourist activity, with many hotels, cafés, and restaurants serving visitors from around the world.

Makrygianni uniquely combines historical heritage with modern urban life. Its views of the Acropolis and direct access to major cultural monuments make it one of the most iconic areas in Athens.